"I'm not sure if I'm really going to do it," he said after the 7-3 loss to the Cleveland Indians. "It depends on how I finish my year. I've already given everything to the game. It will be a difficult decision for me, but I think this is probably going to be it."
The 43-year-old is in his 22nd major league season. His Gold Glove total is the second-most by a shortstop behind only Ozzie Smith, who has 13.
Vizquel doesn't want to commit to a decision.
"We have to get to that point," he said. "I'm going week by week, month by month. I'm not really saying anything that I'm going to right now, but that's probably a possibility."
He moved into a tie with Luis Aparacio, his boyhood idol and fellow Venezuelan, for the second-most career hits by a shortstop with 2,674 on Monday night.
Vizquel played for the Indians from 1994-2004 and was a mainstay on the teams that won six AL Central titles.
Vizquel signed with the White Sox in November but has played in only 14 games and is hitting .200.
He spent last season with Texas, where he appeared in only 62 games.
"I've been playing a couple of times a week," Vizquel said. "That's hard to do."
Vizquel's hit total as a shortstop is second only to New York's Derek Jeter, who entered the week with 2,782. Vizquel has 2,713 career hits, good for 58th place on the all-time list.
Vizquel began his career with Seattle in 1989 before being traded to Cleveland following the 1994 season. He played with San Francisco from 2005-08.