The NBA's Rookie of the Year last season, Rose was held out of Tuesday night's game against the Milwaukee Bucks. He has not played since the preseason opener against Indiana on Oct. 2.
Forward Tyrus Thomas also missed his third game of the preseason because of a sore right hip stemming from a charge he took against the Pacers. The Bulls were also without center Brad Miller, who has the flu and will not travel to Minnesota for Wednesday's game.
Bulls coach Vinny Del Negro said Rose and Thomas are getting better and hopes they can practice Thursday.
"For sure Tyrus," he said. "Derrick's day-to-day, but he feels a lot better every day. We're being a little bit more cautious than anything, but I expect him to get out there Thursday and practice."
Del Negro did not rule out Thomas playing Wednesday, saying, "I want to see how he works out before the game."