The exploratory surgery will be done Wednesday in Los Angeles. Wade felt discomfort last week, and the 26-year-old righty was on the disabled list twice last year with shoulder trouble.
Wade pitched in 27 games for the Dodgers last year and had a 5.53 ERA. As a rookie in 2008, he led Dodgers relievers with 71 1/3 innings and became the team's main setup man for a stretch.
Considered to be a strength of the team, the Dodgers' bullpen has already experienced a number of issues this spring. Along with Wade's injury, right-hander Ronald Belisario still has not resolved visa problems in his native Venezuela.
General manager Ned Colletti does not know when Belisario will be in camp and does not think the 27-year-old will be ready for Opening Day.
Left-handed setup man George Sherrill overcame a sore knee early in camp, but has struggled in exhibition games.
Wade initially was expected to be out for two weeks when his shoulder problems started. Two MRI exams showed that he doesn't have labrum or rotator cuff damage.