Lowrie was sent to Boston for tests to determine the extent of the injury.
"We want to be more conclusive with what's going on," Red Sox manager Terry Francona said. "He showed up yesterday and said it was bothering him. We realized we need to get it checked out."
Lowrie played with an injured left wrist for much of the second half of last season, although Francona said he wasn't sure if it was in the same place.
"He said it started bothering him a couple of weeks ago," Francona said. "From all I heard it was necessary to let the thing calm down."
Lowrie was stuck in a 1-for-18 rut to begin the season after hitting .343 with three homers and 16 RBIs in spring training.