The move is retroactive to Aug. 14, the day after Hampton left a start in Florida with shoulder soreness. The Astros said before making the move on Tuesday that Yorman Bazardo (0-0) will take Hampton's start against Florida on Wednesday.
Hampton (7-10, 5.30 ERA) has started 21 games this season, his highest total since 2004. He missed the 2006 and 2007 seasons after separate elbow surgeries.
Paulino (2-6, 7.28 ERA) has started 11 games for Houston this season. He had a 3.12 ERA in seven appearances at Round Rock.