Drew was out of the lineup Monday night in St. Louis for the second time in three games.
The Diamondbacks don't believe the injury is serious, but manager A.J. Hinch says Drew might sit another day to recover. Drew told Hinch he twisted his knee in the batter's box on a hit-and-run single on Friday.
Hinch had Drew in the lineup batting second before players arrived, then inserted Tony Abreu several hours before Arizona played the Cardinals.