The Tigers (49-49) have reached .500 by winning 12 of 18 -- including three of five against Minnesota and two of three against the AL Central-leading White Sox in the past week -- and still have hope of reaching the postseason.
"That's the biggest thing," Bonderman said. "This is a team, not an individual game. Hopefully we can come out of this road swing a couple games ahead of .500 and be right there in the wild-card chase."
Bonderman (13-6) is second in the AL in wins, trailing only 15-game winner Jon Garland of Chicago. The 22-year-old right-hander allowed two runs, seven hits and two walks while striking out six.
"If he stays healthy, he's going to be one of the best -- ever," said teammate Rondell White, who has played in the majors since 1993.
Guillen said Bonderman will win at least 20 games and then favorably compared him to former Seattle teammate Freddy Garcia.
"I was with Freddy when he was young, and right now [Bonderman] is better," Guillen said.
"I always liked the kid," Hunter said. "What is scary is, he's only going to get better."
Bonderman and Farnsworth were both eligible to pitch while appealing the suspensions they received for their roles in last Sunday's brawl with Kansas City.
Bonderman just missed his third complete game in a little more than a month. He went the distance on July 1 against the Yankees and June 21 against the Twins. He has lasted at least eight innings in five of his last seven starts.
"Not only is he physically gifted, but mentally he's showing signs," Tigers manager Alan Trammell said. "You're talking about a young man that has grown up this year."
The Twins (53-45) slipped into a tie with Oakland atop the wild-card standings -- four games ahead of Detroit -- with their 11th loss in 18 games.
"We're having a tough time offensively," Minnesota manager Ron Gardenhire said. "We need some punch. We need something."
Since the All-Star break, the Twins have scored two or fewer runs in six of 12 games.
Kyle Lohse (7-9) gave up five runs -- four earned -- and a season-high 11 hits in 5 2/3 innings. Lohse, who walked three, is winless in his last four starts and has not won in his last six against AL Central teams.
"Late in the game, it seemed like they made some adjustments and they were able to get to my stuff," Lohse said.
Chris Shelton's first of three hits was a two-out single in the first, Ordonez followed with a double and Shelton scored the first run when Shannon Stewart was charged with an error for mishandling Ordonez's hit down the left field line.
Ordonez has hit in 17 straight games and is batting .426 with 13 RBI during his streak. The four-time All-Star outfielder had hernia surgery in April, a procedure that kept him out until July 1.
"This is the kind of player we envisioned when we signed him," said Trammell, referring to Ordonez's $75 million, five-year contract. "He's just kind of now getting into baseball shape."
The Twins tied it at 1 in the third with Michael Cuddyer's triple, off Granderson's glove in center, and Stewart's single.
Granderson's two-out RBI triple put Detroit ahead 2-1 in the fourth. He was called up from the minors Friday and hit his first major-league homer during the first game of Saturday's doubleheader.
Guillen led off the fifth with a homer, his first since May 5. Shelton then doubled and scored on Ordonez's single. Granderson's homer in the sixth, a 426-foot shot to right-center, made it 5-1.
Dating to Aug. 23 of last year, Bonderman is 18-9. Over the last two seasons, he is 16-9 after a Tigers loss. ... Lohse has lost his last two starts against Detroit after he was unbeaten in the previous 10. ... The Twins stay on the road, facing the Yankees on Tuesday and Boston on Friday. ... Detroit plays at Seattle on Monday and Oakland on Friday. ... Minnesota's Lew Ford, pinch-hitting in the eighth, snapped an 0-for-21 skid with a single.