ST. PETERSBURG, Fla. (AP) -- Jeff Niemann made quite a first impression.
"I liked the way he never lost his composure," Rays manager Joe Maddon said. "He's got a really good makeup. He pitched really well. It's a great first step for him. He did just a wonderful job his first time out."
Niemann, taken fourth overall in the 2004 amateur draft, was recalled from Triple-A Durham to replace the injured Matt Garza in the rotation. The 6-foot-9 right-hander gave up six hits, one walk and had five strikeouts.
"I'm sure it's going to hit me tomorrow," Niemann said. "I'm not sure if you can envision it like that. I just wanted to go out there, keep us in the game and give us a chance to win."
Niemann missed time each of the previous three seasons due to problems with his throwing shoulder. "It's great to be here now and hopefully stay," he said. "I'm taking nothing for granted out there."
The Rays were held without a hit through four by Brian Burres, but chased the left-hander with two outs in the fifth after scoring six times for a 6-0 lead. Akinori Iwamura drove in a run with a single and Carl Crawford hit a two-run single before Upton's three-run shot on a 3-2 pitch with two outs.
"I wasn't hitting the spots really well," Burres said. "I didn't get my fastball back down in the zone. They just hit the pitches that were up in the zone."
Burres (1-1) allowed six runs and five hits in 4 2/3 innings. He has given up 22 earned runs over 16 1/3 innings in nine career appearances against Tampa Bay.
Nick Markakis hit a solo homer off Niemann in the sixth. He also drew a bases-loaded walk one inning later, when the Orioles scored just once after loading the bases with no outs.
"I'll tell you what, he showed a tremendous amount of poise," Rays catcher Mike DiFelice said. "There's no preparation for your first big-league game, especially a starting pitcher. When you get out there and you throw your first pitch, you just don't know what you're going to get. It's a coin toss. I can't say enough how he handled that first inning."
The Orioles went 1-for-11 with runners in scoring position, and left nine runners on base.
"It would have been nice to put three on the board in the first," Baltimore manager Dave Trembley said. "I think that would have set the tone for the game."
Niemann threw 28 of his 93 pitches during the first.
"I really liked the breaking ball for a strike behind in the count," Maddon said. "That's huge. Really good pitchers are able to throw something other than a fastball in a fastball count for a strike, and that's what he did today."
Niemann is the seventh Tampa Bay pitcher to win his first big-league game. ... Upton's homer was his first since last Sept. 12. ... Markakis was in the lineup one day after jamming his left thumb sliding into second base. ... Garza (right arm irritated nerve) is scheduled for a bullpen session Tuesday. He will likely need a minor league rehab stint before rejoining the team. ... Orioles CF Adam Jones struck out in all four of his at-bats. ... Baltimore returns home after a 2-4 road trip. ... The Rays got all of their runs and hits in the fifth.