TORONTO -- The Chicago White Sox knew it wasn't going to be easy to make a 1-0 lead stand up against the AL East-leading Blue Jays.
Eventually, Toronto hitters proved them right.
Jose Bautista drove in the go-ahead run with an eighth-inning single, and the Blue Jays beat the struggling White Sox 2-1 on Saturday to give rookie right-hander Robert Ray his first major league win.
Ray (1-1) allowed one unearned run and three hits in a career-high eight innings. He walked one and struck out three, before Scott Downs closed it out for his fourth save.
"It's awesome to get called up here and then your first strikeout, but that's the one -- the win -- that you really want," Ray said.
White Sox third baseman Josh Fields said Ray's variety of pitches kept him off-balance.
"He threw three pitches and all three of them he was throwing for strikes and throwing well," Fields said. "When you're getting up there and you're looking for a certain pitch and then he drops another one in on you for a strike, it's kind of a tough day."
Toronto trailed 1-0 to begin the eighth against Chicago reliever Scott Linebrink (1-2) but tied it when Vernon Wells hit a one-out single, stole second and came around on Adam Lind's double into the right field corner.
Linebrink was kicking himself afterward after getting ahead of Lind 0-2.
"It was a change-up down and I'd thrown a couple others down in the same spot," Linebrink said. "If he sees multiple pitches with the same speed in the same spot, eventually he's going to get one."
Lind went to third on a wild pitch and scored when Bautista singled to left.
"We went with our best, but it's tough to hold that team," said White Sox bench coach Joey Cora, who managed in place of Ozzie Guillen. "To win 1-0 against that team would have been tough and obviously it didn't happen."
Cora served as interim manager with Guillen in Chicago for his son's college graduation. Guillen will return Monday.
The White Sox have lost three straight and 10 of 13.
Chicago's only run came in the first, when Scott Podsednik drew a leadoff walk, went to second on a grounder and stole third. He scored when catcher Raul Chavez's errant throw bounced off Podsednik's legs and into foul territory.
For the White Sox, who lost their eighth straight in Toronto, the lead was their first here in 49 innings. The last time Chicago led a game in Toronto was June 3, 2007.
Toronto came in having scored a major league-high 221 runs but struggled early against Bartolo Colon. Bautista singled in the second but was thrown out trying to stretch it into a double, while Marco Scutaro was cut down as he tried to leg out a triple in the third.
Perhaps mindful of those plays, Blue Jays third base coach Nick Leyva opted to stop Chavez at third rather than send him home from first on Scutaro's two-out double in the fifth. Colon kept the Blue Jays scoreless by getting Aaron Hill to fly out.
Colon allowed five hits in five shutout innings before leaving with an upset stomach.
"I don't know what it was," Cora said. "He just couldn't go out there again."
Speaking through an interpreter, Colon said the problem was "nothing serious."
With their offense scuffling, the White Sox moved Podsednik into the leadoff spot and dropped Carlos Quentin from third to sixth. Jermaine Dye moved up from the cleanup spot to bat third while Paul Konerko jumped from sixth to fourth.
The lineup changed again shortly before game time when Quentin was scratched with a sore left heel, the same injury that kept him out of two starts earlier this week.
"After BP he came to me and said he couldn't go," Cora said.
Quentin will be reevaulated by Chicago's training staff before Sunday's game and, if his condition has not improved, he will be sent back to Chicago for treatment.
White Sox OF Brian Anderson (right oblique) went 3 for 6 in a doubleheader with Triple-A Charlotte on Friday and is 5 for 10 in three minor league rehab games. ... With SS Scutaro shifted to the second base side as Thome batted in the seventh, the Blue Jays turned a rare 6-5-3 double play. ... After pinch hitting in the seventh, Toronto's Kevin Millar stayed in the game at third base, his first appearance there since Aug. 11, 2002. ... Toronto Raptors coach Jay Triano attended the game.