Jackson, the NBA's Sixth Man of the Year last season, spent 24 games on the injured list with a strained abdominal muscle.
"It feels good," he said. "I'm just ready. Whatever they ask me to do, I'll go out and do it."
To make room for Jackson, the Kings placed swingman Gerald Wallace on the injured list with a sprained left foot.
"I think it's always good timing coming back," Jackson said. "The biggest thing is I haven't played in seven weeks. I have to try to get back into the groove of things -- pushing the ball and playing defense."
Jackson, averaging 13.9 points, 3.5 rebounds, 2.1 assists and 1.0 steals in 49 games, said he didn't know how many minutes to expect in his first game back.
The Kings, who entered the game with a half-game lead over the Timberwolves atop the Western Conference, will keep a close eye on Jackson, who hesitated to classify himself as fully healthy.
"You never know with this injury," Jackson said. "I could be 100 percent but I could hurt it again. It can always come back. That's the bad thing about it."
Wallace is averaging 2.0 points and 2.0 rebounds in 37 games this season.
The Kings now have all of their regulars healthy, a relief to a franchise that has high hopes of reaching the NBA Finals this season after falling in the second round last year to the Dallas Mavericks.