"It was very important," Conley said of getting the first win. "We're just so young. Even though it is preseason, to us, it's not a preseason game. It's almost like regular season because we've got guys competing and guys trying to get wins."
Charlotte coach Larry Brown continued to bemoan his team's love of jump shots over trying to get to the basket. But the long-range shots weren't falling as the Bobcats were 3-of-16 from 3-point range, part of a 40 percent shooting night from the field.
"We have to teach these jump shooters to dribble-drive and get to the rim," Brown said.
Memphis led by as many as 17 points early in the second half and was still up by 15 early in the fourth quarter. But Memphis stopped running its offense, settling for jump shots and playing one-on-one, and that allowed the Bobcats to pull within 85-79 with just over 4 minutes left.
But Warrick dunked, Conley added a 3-pointer, and Memphis rebuilt the lead to double digits as Charlotte didn't score the rest of the way.
"Guys picked up the pressure, and we didn't give in," Gay said of stopping the Bobcats' fourth-quarter rally.
Grizzlies center Darko Milicic, who missed the first two preseason games with a back strain, started and had two points, and rookie Darrell Arthur, the 27th overall pick in the draft, made his first appearance after nursing a right hamstring strain. Arthur finished with eight points and five rebounds in 16 minutes.
"I was kind of nervous starting out and got three fouls," Arthur said. "As the game went on, I got more confident. I was just trying to get out there and play hard, do some things on the glass."
Nazr Mohammed was a late scratch for Charlotte because of a nagging left hamstring injury.
Charlotte, which was down 40-9 in the first quarter at Orlando on Tuesday night, had a better start against Memphis, but trailed 25-20 after the first quarter, primarily because the Grizzlies ran early and shot 69 percent.
"We have to create easy shots," Memphis coach Marc Iavaroni said. "We're not a great shooting team right now, especially from three. We have to find a way to get to the rim."
Memphis led 48-39 at halftime with Mayo and Gay scoring 12 each. But both teams endured sloppy ball-handling with Charlotte committing 13 turnovers and Memphis 12.
Memphis would end the night with 18 turnovers, but Charlotte committed 24 miscues, leading to 29 Memphis points.
The Grizzlies opened the second half with eight straight points to take a 17-point lead, their largest of the game.
Memphis used the advantage to carry a 77-66 lead into the fourth quarter.
"We are not playing very fluid," said Charlotte forward Sean May, who missed all of last season after microfracture surgery on his right knee. "Emeka (Okafor) and I are still learning how to play with each other. I am still learning how to play with everyone. I am still dealing with trying to get into better shape and doing things that I haven't done in a year.
"That's the good thing about preseason. A lot of players need preseason."