- Brian Windhorst, ESPN.com
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The Heat downgraded James from a game-time decision to doubtful 90 minutes before tipoff and James Jones was started in his place. The Nuggets won 130-102.
Heat coach Erik Spoelstra said the hope is a couple of days off would allow James to return to the lineup Saturday in Chicago when the team closes its five-game road trip against the Bulls.
James suffered the injury Wednesday night in Los Angeles when he rolled his ankle on a drive to the basket in the fourth quarter.
James finished the game, a 111-105 loss to the Clippers, but clearly favored the ankle.
When James arrived at the Pepsi Center he was wearing a flip-flop on his left foot, likely because of swelling in the ankle. Earlier he posted a message on his Twitter account indicating he'd gotten some bad news, writing: "The longer we dwell on our misfortunes, the greater is their power to harm us."
James had suffered a series of ankle sprains during his career and usually it has only caused him to miss a game or two. James said Wednesday night, when he had X-rays that showed no break, that doctors didn't believe it was a serious sprain.
It will be James' first missed game of the season.
Brian Windhorst covers the Miami Heat for ESPN.com.
LeBron James sprained his left ankle Wednesday night and says he will decide Thursday whether he will play in Miami's game at Denver.