Wade skipped the Heat's workout Monday to get treatment on the ankle, which he turned when he landed on Paul Pierce's foot during the second half of the Celtics' 85-82 win. Wade went through all of the team's shootaround Tuesday at Conseco Fieldhouse.
"I'm feeling confident it will be all right in the game," Wade said. "It is not going to be ideal early in the game but hopefully once I get loose I'll be ready to go."
Wade is battling a string of injuries and has been for the past six weeks. He's been dealing with a sprained right wrist, suffered after a fall in Chicago last month, that he said might not heal until the end of the season. He's also battled back issues recently and missed games with a sore knee.
"I got treatment on many different body parts," Wade said. "I'm not crying about it or talking about it, it's basketball. I'll continue to get treatment and try to be as effective as I can to try and get healthy. When I get healthy, I'll be ready to go."
That, when considered in context with comments made by Pierce after the Celtics' win, could be construed as a veiled swipe at Pierce -- though Wade never mentioned Pierce by name.
After Sunday's game, Pierce, who went 0-for-10 from the field, said he injured his right hand in practice Saturday and aggravated the injury during the game. Tests on Pierce's hand and left ankle came back negative Monday.
"Right now, I'm just battling a couple minor injuries to my hand and my foot," Pierce said Sunday. "So I think that really explains my tentativeness and my off-shooting today. I told [Celtics coach] Doc [Rivers] that I really didn't have it today but I just tried to grind it out and thank goodness we came out with a win."
On Tuesday, without mentioning Pierce, Wade said: "My fans never know, the media never really know [the extent of injuries].
"I don't really look for, 'OK guys, I might have a bad night tonight because this is the reason.' I'm not that guy. I've had great games when I haven't felt good at all. I've had bad games when I've felt great. I'm all right, I'm playing."
Asked if he was alluding to Pierce, Wade said, "I didn't say anything."
Brian Windhorst covers the NBA for ESPN.com. Information from The Associated Press was used in this report.