Wooden's shot gave the Mean Green (8-3, 1-1 Sun Belt Conference) a road victory over the Hilltoppers (8-4, 0-1) in a battle of the only two teams in the conference with winning records.
Western Kentucky led 85-84 on two free throws by guard Tyrone Brazelton with 18.5 seconds to play. After each team took a timeout with nine seconds remaining, North Texas in-bounded the ball and worked it to Wooden on the block for the decisive shot.
Western Kentucky had a final chance, but Brazelton's driving shot from 15 feet was no good.
North Texas led by 10 points with 11:56 to play and was in control for much of the game. Western Kentucky never led by more than three.
The Mean Green dominated on the boards, holding a 48-25 edge overall, including a 19-9 edge on the offensive boards.
Michael Sturns finished with a game-high 24 points to lead North Texas before fouling out with 51.3 seconds to play. Calvin Watson finished with 21 points and nine rebounds, while Wooden scored 17 points.