Eric Hayes added 16 points for Maryland (6-3). The Terrapins never trailed, but couldn't pull away from the pesky Colonels (7-3) until Hayes hit a 3-pointer to spark a game-ending 11-4 run.
Vasquez began the game on the bench after showing up late for the morning shootaround. The senior guard had started 80 straight games, a streak launched during his freshman season.
Vasquez entered with 14:14 left in the first half. He scored 13 points after halftime, including a huge 3-pointer that put Maryland up 68-62 with 6:18 remaining.
Justin Stommes led Eastern Kentucky with 16 points. The Colonels placed five players in double figures.