The Leopards (11-6, 2-0 Patriot League) had their highest point total of the season while winning their fourth straight game and seventh of their last eight. Mintz was 7-for-10 from the floor and 8-for-9 from the foul line. Willen, the reigning Patriot League Player of the Week, was 6-for-8 from the floor.
Lafayette outshot Colgate 56.6 percent (30-for-53) to 48.1 percent (26-for-54) despite 31 points from the Raiders' Kyle Roemer, who was 11-for-11 from the foul line.
The Leopards were 9-for-20 from 3-point range and made 26 of 36 free throws. Lafayette never let Colgate closer than nine points in the second half and led 81-58 with 9:16 left.
Yaw Gyawu added 22 points for the Raiders (5-11, 1-1), who snapped a four-game winning streak.