Vines hit seven 3-pointers and Jenkins went 9-for-10 from the free throw line for the Pride (14-13, 7-8 Colonial Athletic Association), who have won back-to-back games and five of their last six.
The Pride (83.3 percent) outshot the Seahawks (58.3 percent) at the free throw line, but UNC-Wilmington had a 43.8 percent mark on 3-pointers. Hofstra finished just 39.1 percent from beyond the arc.
The Seahawks led 6-2 less than 2 minutes into the game, but the Pride put together a 19-6 run and never trailed again. Vines hit two straight 3-pointers to help spark the spree.
Ahmad Grant paced the Seahawks (8-18, 4-11) with 23 points.