It was the fourth straight victory for the Terrapins, who trailed 31-16 in the first half and 52-40 shortly after halftime. Jordan Williams scored 18 and Eric Hayes added 15 for Maryland, which solidified its hold on second place in the Atlantic Coast Conference.
The Terrapins (20-7, 10-3) improved to 14-1 at home, including 7-0 in the ACC.
Demontez Stitt led Clemson with 15 points. The Tigers (19-8, 7-6) appeared poised to win a fourth straight ACC game for the first time since 1996-97 before Maryland took control with a 12-0 run.
The Terps trailed 67-65 before Williams made two free throws. Vasquez then drilled a 3-pointer with 7:24 to go, putting Maryland up 70-67 -- its first lead since 14-12.