The Paladins (7-2) trailed 27-23 at halftime and didn't take the lead until the 9:29 mark of the second half, 42-41. Miller and Sebirumbi combined to score eight of Furman's next 10 points as the Paladins took a 52-41 lead with 3:34 left to play.
Andy Diaz hit a free throw with 10:02 left to give the Ospreys a 41-40 advantage, but North Florida missed its next four shots from the field, failing to score until Jerron Granberry's 3-pointer with 2:39 left.
The Ospreys (4-7) turned the ball over seven times during that stretch and trailed 52-43 before Granberry's 3.
Diaz led North Florida with 14 points, while Parker Smith added 10 for the Ospreys, who have lost four in a row.