FGCU (3-7) finished 34 of 60 from the field (56.7 percent), including 11 for 21 from 3-point range (52.4 percent).
Marlon Rivera dished out a career-high 12 assists for FGCU, which snapped a six-game losing streak.
N.C. Central trailed 39-28 at halftime despite going 12 for 25 from the floor (48 percent) in the opening half. FGCU stretched its lead to as many as 26, 75-49, with 6:35 left to play.
N.C. Central has lost by an average of 18.7 points during its three-game losing streak.