Ware made 4 of 9 3-pointers and 12 of 14 free throws and Larry Anderson scored 11 points for the 49ers (19-10, 13-2), who won their season-high eighth straight as they played their first game since clinching the Big West Conference regular-season championship.
Orlando Johnson scored 18 points for the Gauchos (14-13, 7-8), who lost their third in a row.
Long Beach State outrebounded UC Santa Barbara 49-29 and made 21 of 28 free throws to just 5 of 8 for the Gauchos.
Two pairs of free throws by Ware bracketed a basket by Brandon Nevens as the 49ers turned a 24-24 tie into a 30-24 edge with 1:17 left in the first half. They led 32-29 at halftime.