The 65-point margin of victory by the Bulldogs (6-11) is the largest in school history, eclipsing the previous mark set when Yale defeated Lyndon 101-37 on Nov. 7, 2011.
Yale never trailed in the contest against Oberlin (4-10), a Division III team. The Bulldogs went on a 16-0 run that was capped by Jack Montague's layup to give them a 41-15 lead with 1:17 left in the first half.
Yale shot 69.1 percent (38-55) from the floor and made 13 3-pointers.
Geoff Simpson was the only Oberlin player to score in double figures with 14 points.