Saunders shot 7-of-9 from the field while Moundou-Missi was 10-of-15 and led the Crimson (4-0) with nine rebounds. Harvard shot 57.1 percent from the field.
Dyami Starks came into the game for Bryant (2-2) as the nation's leading scorer with 100 points through three games, but was held by Harvard to just 11 points.
Bryant trailed by 8 with nine minutes to play but Harvard went on a 13-2 run to extend its lead to 76-57.
Bryant shot just 2-of-13 from behind the 3-point arc and had 11 shots blocked by the Crimson. Alex Francis led the Bulldogs with 17 points.