| 1st Quarter | | FSU | CLEM |
| Florida State at 15:00 | FSU | CLEM |
| | Dustin Hopkins kickoff for 68 yards returned by C.J. Spiller for 23 yards to the Clem 25. | 0 | 0 |
| Clemson at 14:45 | FSU | CLEM |
| 1st and 10 at CLEM 25 | C.J. Spiller rush for 4 yards to the Clem 29. | 0 | 0 |
| 2nd and 6 at CLEM 29 | C.J. Spiller rush for 5 yards to the Clem 34. | | |
| 3rd and 1 at CLEM 34 | Kyle Parker pass complete to Chad Diehl for 7 yards to the Clem 41 for a 1ST down. | | |
| 1st and 10 at CLEM 41 | Kyle Parker pass incomplete to Jacoby Ford. | | |
| 2nd and 10 at CLEM 41 | Kyle Parker pass complete to C.J. Spiller for 4 yards to the Clem 45 out-of-bounds. | | |
| 3rd and 6 at CLEM 45 | Kyle Parker pass incomplete to Jacoby Ford. | | |
| 4th and 6 at CLEM 45 | Dawson Zimmerman punt for 40 yards, returned by Greg Reid for 42 yards to the Clem 43. | | |
| DRIVE TOTALS: CLEMSON drive: 6 plays 20 yards, 02:39 CLEMSON PUNT |
| |
| Florida State at 12:21 | FSU | CLEM |
| 1st and 10 at CLEM 43 | Christian Ponder rush for 4 yards to the Clem 39. | 0 | 0 |
| 2nd and 6 at CLEM 39 | Jermaine Thomas rush for 5 yards to the Clem 34. | | |
| 3rd and 1 at CLEM 34 | Christian Ponder rush for 1 yard to the Clem 33 for a 1ST down. | | |
| 1st and 10 at CLEM 33 | Christian Ponder pass complete to Rod Owens for 7 yards to the Clem 26. | | |
| 2nd and 3 at CLEM 26 | Jermaine Thomas rush for 5 yards to the Clem 21 for a 1ST down. | | |
| 1st and 10 at CLEM 21 | FLORIDA ST penalty 10 yard Holding on David Spurlock accepted, no play. | | |
| 1st and 20 at CLEM 31 | Jermaine Thomas rush for 10 yards to the Clem 21. | | |
| 2nd and 10 at CLEM 21 | Christian Ponder sacked by Brandon Maye for a loss of 1 yard to the Clem 22. | | |
| 3rd and 11 at CLEM 22 | FLORIDA ST penalty 10 yard Holding on Beau Reliford accepted, no play. | | |
| 3rd and 21 at CLEM 32 | Christian Ponder pass complete to Bert Reed for 15 yards to the Clem 17. | | |
| 4th and 6 at CLEM 17 | Dustin Hopkins 35 yard field goal GOOD. | 3 | 0 |
| | Dustin Hopkins kickoff for 67 yards returned by C.J. Spiller for 21 yards to the Clem 24. | | |
| DRIVE TOTALS: FLORIDAST drive: 8 plays 26 yards, 04:46 FLORIDAST FG |
| |
| Clemson at 7:02 | FSU | CLEM |
| 1st and 10 at CLEM 24 | Jacoby Ford rush for 8 yards to the Clem 32. | 0 | 0 |
| 2nd and 2 at CLEM 32 | C.J. Spiller rush for 14 yards to the Clem 46 out-of-bounds for a 1ST down. | | |
| 1st and 10 at CLEM 46 | Kyle Parker pass complete to Xavier Dye for 11 yards to the FlaSt 43 for a 1ST down. | | |
| 1st and 10 at FSU 43 | Kyle Parker pass complete to Michael Palmer for 5 yards to the FlaSt 38. | | |
| 2nd and 5 at FSU 38 | C.J. Spiller rush for a loss of 2 yards to the FlaSt 40. | | |
| 3rd and 7 at FSU 40 | Kyle Parker pass complete to Jacoby Ford for 23 yards to the FlaSt 17 for a 1ST down. | | |
| 1st and 10 at FSU 17 | Kyle Parker pass complete to Dwayne Allen for 17 yards for a TOUCHDOWN. | 3 | 6 |
| | Richard Jackson extra point MISSED. | | |
| | Spencer Benton kickoff for 68 yards returned by Chris Thompson for 20 yards to the FlaSt 22. | | |
| DRIVE TOTALS: CLEMSON drive: 7 plays 76 yards, 03:09 CLEMSON TD |
| |
| Florida State at 3:53 | FSU | CLEM |
| 1st and 10 at FSU 22 | Christian Ponder pass complete to Bert Reed for 9 yards to the FlaSt 31. | 3 | 6 |
| 2nd and 1 at FSU 31 | Lonnie Pryor rush for 2 yards to the FlaSt 33 for a 1ST down. | | |
| 1st and 10 at FSU 33 | Jermaine Thomas rush for 3 yards to the FlaSt 36. | | |
| 2nd and 7 at FSU 36 | CLEMSON penalty 15 yard Personal Foul on Jarvis Jenkins accepted. | | |
| 1st and 10 at CLEM 49 | Christian Ponder pass complete to Lonnie Pryor for 49 yards for a TOUCHDOWN. | 9 | 6 |
| | Dustin Hopkins extra point GOOD. | 10 | 6 |
| | Dustin Hopkins kickoff for 69 yards returned by C.J. Spiller for 27 yards to the Clem 28. | | |
| DRIVE TOTALS: FLORIDAST drive: 4 plays 78 yards, 01:45 FLORIDAST TD |
| |
| Clemson at 2:08 | FSU | CLEM |
| 1st and 10 at CLEM 28 | C.J. Spiller rush for a loss of 3 yards to the Clem 25. | 10 | 6 |
| 2nd and 13 at CLEM 25 | Kyle Parker pass complete to Michael Palmer for 2 yards to the Clem 27. | | |
| 3rd and 11 at CLEM 27 | Kyle Parker pass intercepted by Jamie Robinson at the FlaSt 48, returned for 52 yards for a TOUCHDOWN. | 16 | 6 |
| DRIVE TOTALS: CLEMSON drive: 3 plays -1 yards, 01:44 CLEMSON INT |
| |
| Florida State at 0:24 | FSU | CLEM |
| | Dustin Hopkins extra point GOOD. | 17 | 6 |
| | Dustin Hopkins kickoff for 33 yards returned by Kasey Nobles for 8 yards to the Clem 45. | | |
| DRIVE TOTALS: FLORIDAST drive: 0 plays 0 yards, 00:00 FLORIDAST TD |
| |
| Clemson at 0:24 | FSU | CLEM |
| 1st and 10 at CLEM 45 | C.J. Spiller rush for a loss of 2 yards to the Clem 43. | 17 | 6 |
| | End of 1st Quarter | | |
Florida State 24, 
Clemson 40