Frazier was 14-of-24 for 244 yards without an interception,
Mathis had five catches for 146 yards and Coleman gained 80 yards
on 16 carries.
The Pirates (2-1) rolled up 506 yards of offense on 78 plays
while holding the Golden Tigers (2-2) to 80 yards and 48 plays.
Hampton amassed 212 yards rushing on 51 carries to 18 for Tuskegee
on 29 attempts.
Hampton had a total of six sacks on three Tuskegee quarterbacks
and did not commit a turnover while forcing three.
Frazier and Mathis combined on touchdown passes of 13, 67 and 3
yards in the first half as Hampton took a 29-0 halftime lead.
Coleman had scoring runs of 22 and 5 runs in the Pirates' 24-point
Cortland Florence led Tuskegee with 35 yards rushing on 11
carries. Ralph Gordon was 5-of-12 passing for 56 yards.
The game was played as part of the city's four-day celebration
of historically black colleges. It was the first non-professional
football game at Cleveland Browns Stadium since it opened in 1999.