St. Francis (0-5) opened the scoring with a six-play, 35-yard scoring drive capped by George Little's 1-yard sneak with 2:13 left in the first quarter. Antoine Rivera set up the drive with a 17-yard punt return.
Duquesne (4-2) scored its first points on a 25-yard field goal by Mark Troyan with 6:05 left in the first half. The field goal capped a seven-play, 48-yard drive.
The Dukes put together a 10-play, 58-yard drive to open the second half, but were stopped on downs at the St. Francis 25. Duquesne's next possession needed only one play, as Rombach connected with Sean Bunovich on a 63-yard touchdown pass. The score came with 8:31 left in the third quarter.
Two possessions later, Rombach connected with Bruce Hocker on an 18-yard touchdown pass. The score capped a four-play, 40-yard drive and gave Duquesne a 17-7 lead.
St. Francis cut the deficit to seven points with a 28-yard field goal by Adam Sciulli with 8:15 left in the game. The score came after an interception and return of 27 yards by the Red Flash's Matthew Parker.
Duquesne scored its final touchdown on its next possession, as Knapp connected with Conrad Carter on a 49-yard touchdown pass with 6:37 left on the clock. Rombach completed 12 of 25 passes for 230 yards. Knapp was 5 of 10 for 74 yards,
St. Francis drove 60 yards on eight plays on its final possession and scored on 2-yard pass from Little to Omar Winston with 3:34 left. Duquesne ran out the clock on its final possession.
Little was 19 of 32 for 141 yards.