LITTLE ROCK, Ark. -- Ryan Mallett threw for 313 yards and five touchdowns to lead Arkansas over Mississippi State 42-21 on Saturday.
Mallett's final touchdown pass was his 28th of the season, a school record. Clint Stoerner held the old mark of 26.
Anthony Dixon rushed for 176 yards for Mississippi State, which was eliminated from bowl contention.
The Bulldogs (4-7, 2-5 Southeastern Conference) ran all over the Razorbacks (7-4, 3-4) in the third quarter, cutting the Arkansas lead to 28-21 after Dixon's 70-yard scoring run. Mississippi State had the ball near midfield toward the end of the period, but Dixon fumbled and Elton Ford recovered for the Razorbacks.
Mallett threw an 11-yard touchdown pass -- off his back foot while scrambling from pressure -- to Greg Childs to make it 35-21 early in the fourth.
Mallett is the only Arkansas player to throw for five touchdowns in a game, which he has done three times this year. He also holds the school record for yards passing in a season.
Arkansas began the game on a sour note when Mallett was intercepted on his second pass. Mississippi State mishandled its first snap, but wide receiver Chad Bumphis picked up the ball in the backfield and ran all the way to the Arkansas 3 for a 49-yard gain. Arnil Stallworth's 1-yard touchdown run made it 7-0.
Mallett's 5-yard touchdown pass to Jarius Wright gave the Razorbacks a 21-7 halftime lead.
Dixon's 4-yard scoring run pulled Mississippi State to within seven early in the second half, but Mallett answered with a 64-yard strike to Hamilton. The third-and-long play started as a simple slant, but Hamilton eluded two tacklers and outran the defense for a touchdown.
Arkansas announced before the game that running back Michael Smith will miss the rest of the season with an injured hamstring. The Razorbacks were outrushed 327-83.
Broderick Green ran 2 yards for the game's final touchdown with 2:35 remaining.