EAST LANSING, Mich. (AP) -- Drew Stanton passed for 244 yards and two touchdowns and ran for another TD to lead Michigan State to a 46-15 win over Indiana on Saturday.
The win keeps bowl hopes alive for the Spartans (5-3, 2-3 Big Ten), who ended a three-game losing streak. Michigan State needs to win one of its last three games to be eligible for a bowl.
The loss hurts postseason chances for the Hoosiers (4-4, 1-4 Big Ten), who haven't been to a bowl since 1993 -- the longest drought in the Big Ten.
Michigan State entered Saturday's game ranked in the top 15 in the nation in five different offensive categories. The Spartans gained 493 yards of total offense against the Hoosiers.
Michigan State also got help from its special teams, as Demond Williams returned the opening kickoff 98 yards for a touchdown. Williams also blocked a PAT attempt, which Ashton Watson returned for a defensive two-point conversion to give the Spartans a 25-8 halftime lead.
The Spartan defense contributed with interceptions by SirDarean Adams, Eric Smith and Otis Wiley and a fumble recovery by Brandon Long. Each turnover killed an Indiana drive.
Stanton completed 17-of-31 passes with one interception for the Spartans. Stanton rushed for 27 yards on 10 carries. He sat out most of the fourth quarter.
Michigan State running back Javon Ringer gained 109 yards on 11 carries, including a 45-yard TD run to give the Spartans a 39-8 lead late in the third quarter.
Kerry Reed caught six passes for 80 yards, including a 3-yard TD pass, for the Spartans.
Indiana quarterback Blake Powers completed 20 of 35 passes for 198 yards. He threw a 23-yard touchdown pass to James Hardy but also had three interceptions. Hardy also caught an 11-yard TD pass from backup quarterback Graeme McFarland as time expired.
Indiana got on the scoreboard with a safety early in the first quarter. But the Hoosier offense struggled to get untracked.
Michigan State has won eight of its last nine games with Indiana, including four straight. The Spartans lead the overall series, 38-14-2, including a 20-6-1 record in East Lansing.
The teams have played for the Old Brass Spittoon since 1950. The spittoon, recovered from one of Michigan's earliest trading posts, is believed to be about 150 years old.