STILLWATER, Okla. -- Keith Toston ran for a career-best 148 yards and Oklahoma State had the second trio of 100-yard rushers in school history in the Cowboys' 57-13 win over Missouri State on Saturday.
Beau Johnson rushed for 138 yards, and Kendall Hunter added 132 more as Oklahoma State (3-0) piled up 450 yards rushing, sixth-most in school history. Hunter also topped 100 yards along with Dantrell Savage and Zac Robinson in last year's 49-45 win against Texas Tech.
Hunter scored on runs of 8 and 4 yards in the first half and passed the 100-yard mark on a 35-yard scamper that set up his second touchdown. He has passed the century mark in his first three starts, including a career-best 210 yards last week against Houston.
Johnson also had two touchdown runs and Toston scored on a 15-yard run. The Cowboys had their highest rushing total since 1988, Barry Sanders' Heisman Trophy season.
Starting quarterback Zac Robinson threw only four passes, completing two for 82 yards, before yielding to Alex Cate on the final drive of the first half. Cate and fellow backup Brandon Weeden both saw their first action of the season.
Dez Bryant, who caught nine passes for 236 yards and three touchdowns against Houston, dropped the only pass thrown in his direction.
The margin of victory was the largest for Oklahoma State since Mike Gundy took over as coach to start the 2005 season. The Cowboys won two games by 42 points the following year, including a 52-10 win against Missouri State in the teams' last meeting.
The Bears (0-2), a Championship Subdivision opponent that lost to Division II school Washburn in their opener, fell to 1-22 against Bowl Subdivision foes. The only win was a 31-24 upset of UNLV in the 1990 season opener.
Missouri State's day was rocky from the start. Kingjack Washington fumbled on the first play from scrimmage and Oklahoma State's Derek Burton pounced on the ball, setting up the Cowboys on their own 18-yard line for a short scoring drive that ended with Robinson's 1-yard sneak.
A false start penalty squelched the Bears' thoughts of going for it on fourth-and-1 on their next possession and also put them just out of range for kicker Matt Hottelman, who missed a 51-yard field goal. Robinson connected with Bo Bowling for a 66-yard score on the very next play, and the rout was on.
The Bears got their first points on Hottelman's 49-yard field goal that was set up after Robinson had to take a 31-yard loss when a shotgun snap went over his head. Tailback Beau Johnson fumbled on the next play to put Missouri State in field-goal range.
Kickoff was moved up by six hours to keep it from being affected by Hurricane Ike's remnants. There was a light rain at the start, but most of the game was played under overcast skies.