The Bulls beat Washington anyway, and the Hawks settled for sixth and will face No. 3 Indiana in the first round.
"They are a good team and it is going to take a heck of an effort to beat them in a seven-game series," Hawks coach Larry Drew said.
Anthony finished with 28.7 points per game to end Kevin Durant's three-year run as scoring champion. Durant also sat out Wednesday and stayed at 28.1 per game, making Anthony the first Knicks player since newly elected Hall of Famer Bernard King in 1984-85 to lead the league.
But it was an otherwise bad day in a strong regular season for the Knicks, as Rasheed Wallace retired again earlier Wednesday because of continued pain in his left foot.
Sidelined since December, Wallace came back Monday against Charlotte but lasted just 4 minutes before pulling himself out.
He had quickly become a key contributor on the court and an important leader in the locker room after ending a two-year retirement to join the Knicks. He was at the game sitting behind the bench, and coach Mike Woodson said he hopes the 38-year-old forward will hang around.
Guard Pablo Prigioni, who had moved into the starting lineup late in the season, sprained his right ankle in the first quarter and didn't return. The Knicks said X-rays were negative and Woodson said he wasn't sure if Prigioni would be ready for Saturday's game.
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Shumpert motioned to come out of the game immediately after throwing a lob pass on the fast break in the fourth quarter and remained on the bench for the rest of the game. His injury was just a cramp and he said afterward he was fine. Copeland hurt his shoulder but kept shooting through the pain, going 14 of 29 in his second straight 30-point performance.
James White scored 20 points for the Knicks and Shumpert had 18. Earl Barron, signed earlier Wednesday, finished with 11 points and 18 rebounds.
Mike Scott had 23 points and 14 rebounds for the Hawks, who lost their final two games. John Jenkins scored 20 points.
Quentin Richardson, signed Tuesday by the Knicks, scored five points on 1-of-11 shooting and grabbed 10 rebounds. ... New York swept the series for the first time since 2003-04 and has won the past four meetings. ... Referee Courtney Kirkland appeared to injure his left knee in the fourth quarter and had to be helped to the bench.
MVP: Chris Copeland burned the Hawks' defense with strong play on the perimeter and in the paint. He paced the Knicks' offense all night and ignited the initial run that put New York in front by double digits. He finished the night with 33 points.
LVP: DeShawn Stevenson is known to be anemic offensively, but Wednesday night he was even worse than his reputation. He shot contested jumper after contested jumper, finishing the night 1-for-11. He missed all six of his attempted 3-pointers and failed to provide any defensive resistance.
X factor: James "Flight" White and Iman Shumpert. Although Copeland provided the preliminary spark, White and Shumpert kick-started several runs. Shumpert finished with 18 points, eight assists and seven rebounds, while White finished with 20 points and six rebounds.