Smith, who played 10 seasons for Jacksonville, was pulled over on Interstate 95 in Jacksonville for excessive window tint on his 2009 Mercedes Benz, Florida Highway Patrol Lt. Bill Leeper said.
The trooper reported that the inside of the car smelled like burnt marijuana. During a search, the trooper found crack cocaine, marijuana and a business card with powder cocaine residue in the car's center console.
Smith faces multiple drug charges, plus a charge of driving with a suspended license. He was being held at the Duval County Jail with no bond set.
Smith retired from the Jaguars in 2006 after playing from 1995 to 2005. He finished with 862 receptions and 12,287 receiving yards and 67 touchdowns. He was a five-time Pro Bowl selection.
Despite the exceptional stats, Smith's career was not without problems.
In 2001, he had three operations to remove scar tissue from his abdomen. Some questioned whether he would play again, but he caught 112 passes for 1,373 yards -- despite being arrested in November that year for suspicion of drunken driving. Tests later revealed he had cocaine in his system. He vehemently denied using the drug.
He was suspended for the first four games of the 2003 season for violating the league's substance-abuse policy. He then publicly acknowledged an addiction and spent several weeks in rehab.
Smith also had problems before joining the Jaguars.
The third receiver selected in the 1992 draft behind Desmond Howard and Carl Pickens, Smith broke his leg and missed most of his rookie season. In 1993, he needed an emergency appendectomy and suffered through infection and stomach problems. He missed the entire year. He didn't play in 1994 after getting cut by Dallas and Philadelphia.
In 1995, he caught on with the expansion Jaguars after his mother sent coach Tom Coughlin a binder of press clippings to help him earn a tryout.
He made the most of his chance, teaming with Keenan McCardell to help land the Jaguars in the playoffs in only their second season.