Odom was the Bengals' top pass rusher, tied for the league lead with eight sacks. He hurt his right Achilles tendon during a 28-17 loss to Houston on Sunday. The Bengals put Odom on injured reserve, but didn't immediately fill his spot.
He wasn't the only defensive lineman hurt. Domata Peko suffered a knee injury on the opening series and didn't return. Coach Marvin Lewis declined to provide any information on that injury Monday, other than to say that "it's not believed to be real severe."
With so many starters hurt, the line is an injury-depleted mess.
"Just the fact that I've got two good legs is a blessing," said Johnson, who has plantar fasciitis in his right foot. "It's tough. Guys are banged up. It is what it is, and we're going to play through it."
The defensive line is the second area wiped out by injuries this season. The Bengals lost their top two tight ends for the season when Reggie Kelly tore an Achilles tendon and Ben Utecht suffered a major concussion during training camp. Their backups have struggled, repeatedly dropping passes.
Now, the defensive line -- a key to their 4-2 start -- is missing its best player and will have to turn to backups to pull it through. The Bengals host the Bears (3-2) on Sunday.
"Antwan has done some things this year that no one's done," Johnson said Monday. "He's a great player and a great asset to our defense. Antwan has a lot of natural ability. He can reach over five people and grab you with his long arms."
Rookie defensive end Michael Johnson, a third-round pick who has played on passing downs, is likely to get an expanded role.
"Every week he gets quite a few snaps," Lewis said. "I think Michael played his best football that he played this season yesterday. Hopefully that continues as a trend. He'll have an opportunity to do more and more."
The defense had by far its worst game of the season on Sunday, a week after it played its best. The Bengals dedicated their 17-14 win at Baltimore to the family of defensive coordinator Mike Zimmer, whose wife, Vikki, died a few days earlier. The inspired defense allowed only one touchdown.
Against the Texans, the Bengals were sloppy. Matt Schaub repeatedly completed passes to wide-open tight ends and running backs, and threw receiver screens that went for long gains. Houston rolled up 26 first downs and 472 yards, the third-highest total in franchise history.
Tank Johnson dismissed suggestions that the defense had a letdown after the emotional game in Baltimore.
"Everybody's talking about this emotional stuff? Why is everybody so emotional?" Johnson said. "We're fine. We're grown men. You deal with stuff and you move on."
The Bengals had won four in a row, the last three against AFC North rivals. By beating Pittsburgh, Cleveland in overtime and Baltimore, they moved into sole possession of first place for one week. The loss on Sunday left them tied with Pittsburgh.
Quarterback Carson Palmer also shrugged off suggestions the Bengals were flat after those three emotional division wins.
"That's just making an excuse," Palmer said. "We played three emotional games -- one game went five whole quarters -- but if we start pointing fingers and using excuses like that, that doesn't make us better. That's a negative mindset."