Steve Smith: Smith continued his breakout season in Week 4. The third-year wideout, who has caught at least one touchdown pass in three straight games, had 11 catches for 134 yards and two TDs in the Giants' 27-16 victory over Kansas City. Smith has had double-digit catch totals in two of New York's four games this season.
David Garrard: Taking advantage of a depleted Tennessee secondary, Garrard completed 27 of 37 passes for 323 yards and three TDs to lead Jacksonville to a 37-17 victory over the reeling Titans. It was Garrard's third career 300-yard passing game. The Jaguars had 442 yards of total offense, their most since 2007, and they've scored 30-plus points in back-to-back games.
Peyton Manning: Manning led the Colts to touchdowns on four of their first five drives Sunday and extended Indianapolis' regular-season winning streak to 13 with a 34-17 victory over Seattle. Manning, who's now tied with Fran Tarkenton with 342 TD passes (second all time), finished 31-of-41 for 353 yards, marking the first time in 12 NFL seasons he has topped 300 yards in four consecutive games.
Johnny Knox: The Bears' Knox injured his right leg Sunday, but he did plenty of damage to the Lions before exiting the game. Knox opened the third quarter with a 102-yard kickoff return for a score -- the second-longest kickoff return in Bears history. Knox's return broke a 21-21 tie and Chicago pulled away for a 48-24 victory.
The Saints' defense: Thanks largely to a much-improved defense that suddenly has a penchant for making big plays, the Saints improved to 4-0 Sunday. Darren Sharper returned one of his two interceptions of Jets QB Mark Sanchez 99 yards for a score, Will Smith forced a fumble in the end zone to produce a second defensive touchdown, and New Orleans handed the Jets a 24-10 loss.
Rashard Mendenhall: With Willie Parker sidelined with a toe injury, the Steelers needed a big game from Mendenhall. That's exactly what they got. The second-year running back enjoyed a breakout night, rushing for 165 yards and two TDs, in the Steelers' 38-28 victory over San Diego.
Mark Sanchez: Sanchez, who has created a lot of buzz with his strong early play, finally looked like a rookie in Week 4. Sanchez thew three interceptions, including one that was returned 99 yards for a TD, and lost a fumble that resulted in another score, as the Jets fell to New Orleans. It was the first time this season Sanchez did not throw a touchdown pass.
Trent Edwards: Edwards was intercepted three times and sacked six times in Buffalo's 38-10 loss to the Dolphins. Edwards' first interception was returned 23 yards for a score by Miami's Vontae Davis. Edwards finished 14-of-26 for 192 yards, posting a 51.0 rating.
The Raiders' running game: Playing against the league's worst run defense, the Raiders mustered only 45 rushing yards in a 29-6 loss at Houston. Darren McFadden, Oakland's first-round pick in 2008, carried the ball six times for minus-3 yards. The Texans entered Week 4 allowing 205 rushing yards a game.