Manning and the Colts are favored to win next year's Super Bowl, according to odds released Monday by BetUS.com.
The St. Louis Rams, coming off a 1-15 season, are the longest shot on the board at 150-1.
The Colts were 5-point favorites in the Super Bowl on Sunday, but Drew Brees and the Saints rallied for a 31-17 victory. New Orleans sealed the upset when Tracy Porter intercepted Manning's pass and returned it for a touchdown late in the fourth quarter.
Indianapolis is 3-1 to get back to the Super Bowl, while New Orleans is 5-1.