Ailing Edwards will not play in penultimate preseason game
Edwards missed his third straight practice Friday since knocking knees in a collision with running back Marshawn Lynch on Tuesday night.
"It's making minimal progress," Edwards said.
Edwards, who walked with a limp throughout the workout, was optimistic that he'll be ready for Buffalo's final preseason game against Detroit on Thursday.
The Bills host Seattle in their season opener Sept. 7.
Backup J.P. Losman will get the start against the Colts in place of Edwards.
Copyright 2008 by The Associated Press
MORE NFL HEADLINES
- Sources: Bell, Blount to play despite charges
- RG III tweets to naysayers: Keep doubting
- Cowboys doctors tell Holloman (neck) to retire
- Loose sod at 49ers' new stadium removed