| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Peyton Manning |
1. Peyton Manning, QB | IND | W 30-17 vs. NYJ | 26 | 39 | 377 | 3 | 0 | 2 | 0 | 123.6 |
| 2. Brett Favre, QB | MIN | L 31-28 at NO | 28 | 46 | 310 | 1 | 2 | 0 | 1 | 70.0 | |
| 3. Mark Sanchez, QB | NYJ | L 30-17 at IND | 17 | 30 | 257 | 2 | 1 | 0 | 0 | 93.3 | |
| 4. Drew Brees, QB | NO | W 31-28 vs. MIN | 17 | 31 | 197 | 3 | 0 | 1 | 0 | 106.5 | |
| 5. Brad Smith, QB | NYJ | L 30-17 at IND | 1 | 1 | 45 | 0 | 0 | 0 | 0 | 118.8 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Adrian Peterson |
1. Adrian Peterson, RB | MIN | L 31-28 at NO | 25 | 122 | 4.9 | 3 | 27 | 0 | |
| 2. Joseph Addai, RB | IND | W 30-17 vs. NYJ | 16 | 80 | 5.0 | 0 | 17 | 1 | ||
| 3. Pierre Thomas, RB | NO | W 31-28 vs. MIN | 14 | 61 | 4.4 | 1 | 12 | 0 | ||
| 4. Thomas Jones, RB | NYJ | L 30-17 at IND | 16 | 42 | 2.6 | 0 | 12 | 0 | ||
| 5. Shonn Greene, RB | NYJ | L 30-17 at IND | 10 | 41 | 4.1 | 0 | 13 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Pierre Garcon |
1. Pierre Garcon, WR | IND | W 30-17 vs. NYJ | 11 | 151 | 13.7 | 1 | 36 | 0 | |
| 2. Austin Collie, WR | IND | W 30-17 vs. NYJ | 7 | 123 | 17.6 | 1 | 46 | 0 | ||
| 3. Bernard Berrian, WR | MIN | L 31-28 at NO | 9 | 102 | 11.3 | 0 | 30 | 1 | ||
| 4. Jerricho Cotchery, WR | NYJ | L 30-17 at IND | 5 | 102 | 20.4 | 0 | 45 | 0 | ||
| 5. Braylon Edwards, WR | NYJ | L 30-17 at IND | 2 | 100 | 50.0 | 1 | 80 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
David Harris |
1. David Harris, LB | NYJ | L 30-17 at IND | 11 | 0 | 11 | 2.0 | 1 | 0 | 0 |
| 2. Darren Sharper, S | NO | W 31-28 vs. MIN | 7 | 4 | 11 | 0.0 | 0 | 0 | 0 | |
| 3. Scott Shanle, LB | NO | W 31-28 vs. MIN | 8 | 2 | 10 | 0.0 | 0 | 0 | 0 | |
| 4. Tracy Porter, CB | NO | W 31-28 vs. MIN | 8 | 0 | 8 | 0.0 | 1 | 1 | 0 | |
| 5. Kerry Rhodes, S | NYJ | L 30-17 at IND | 7 | 1 | 8 | 0.0 | 0 | 0 | 0 | |
