St. Louis came back after falling behind by a pair of goals and won it on Boyes' magnificent effort that gave the Blues their third straight win and seventh in the last eight games
Going deep into the Buffalo zone on the left wing, Boyes faked out goalie Ryan Miller before lifting the puck toward a gaping net. The shot, though, was knocked out of the air by Daniel Paille and bounced a couple times in the crease. Boyes then rounded the net and swatted the puck in from the other side for his 14th goal and fourth winner.
"I heard no whistle, so I kept playing, and a half-second later the puck popped out," Boyes said. "I made sure that one really went in."
Mike Johnson and Paul Kariya each had a goal and assist, Martin Rucinsky also scored and Boyes added an assist for St. Louis, which won for the second time in eight games when trailing after two periods.
"We thought we were deserving of a win tonight," Blues coach Andy Murray said. "We thought we were good all game even though we were trailing. We liked how we were playing."
The Sabres were fortunate to be up after two periods. Miller kept them ahead with several big stops over the first 40 minutes and finished with 28 saves.
"We didn't look like ourselves, but St. Louis is a tough team to play against," he said. "We had to be better, and we should have known they were going to come hard."
"We turned the puck over way too many times," Sabres coach Lindy Ruff said. "We were very careless with the puck. We didn't take care of it and it hurt us."
The Sabres are winless in their last 11 games against St. Louis -- including eight loses in regulation -- and haven't beaten the Blues at home in more than 12 years.
"We dominated in the second and third," said Legace, who was making his third start in four games. "Our guys were phenomenal. If not for Miller it would have been over in the second."
The Sabres scored first for the sixth straight game when Pominville redirected Clarke MacArthur's pass from the high slot with just 1:21 remaining in the first period for his seventh of the season. It was Pominville's second goal in two games after he was held goal-less for 13 straight games.
Buffalo made it 2-0 at 12:28 of the second period on Kotalik's power-play goal. Standing in the bottom of the left circle, Kotalik one-timed Jaroslav Spacek's cross-ice pass past Legace for his fifth of the season.
St. Louis cut the deficit in half when Rucinsky scored his third with just under five minutes left in the second. From in tight, Rucinsky tapped in Keith Tkachuk's pass.
Kariya tied it 3:45 into the third when he converted a rebound after Miller stopped Tkachuk's shot on a two-on-one. Johnson then gave the Blues their first lead when he scored his first 2:34 later.
Sekera tied it with his first career goal with just under nine minutes left in the third, beating Legace with a slap shot from the left point.
The game also marked the return of former Sabres defenseman Jay McKee. McKee played in Buffalo for nine years before signing with the Blues as a free agent following the 2005-06 season.
Buffalo's last win at home against St. Louis was a 5-2 victory in October 1995. ... Sabres defenseman Henrik Tallinder missed his second game after straining a shoulder against Montreal on Saturday. He's expected to miss at least a week ... Buffalo right winger Drew Stafford returned after missing three games because of a shoulder injury. ... The Blues will play four of their next five on the road. ... All five of Kotalik's goals this season have come on the power play.
Copyright by STATS LLC and The Associated Press
Arena: First Niagara Center Location: Buffalo, New York
Referees: Ian Walsh Linesmen: Greg Devorski, Steve Miller
Attendance: 18,690 (100.0% full)
Team Stat Comparison
Power Play Goals
Power Play Opportunities
Shots on Goal
Jason Pominville (7)
Assists: Clarke MacArthur, Toni Lydman
Ales Kotalik (5)
(Power Play) Assists: Jaroslav Spacek, Tim Connolly
Martin Rucinsky (3)
Assists: Keith Tkachuk, Mike Johnson
Paul Kariya (7)
Assists: Keith Tkachuk, Brad Boyes
Mike Johnson (1)
Assist: Bryce Salvador
Andrej Sekera (1)
Assists: Tim Connolly, Jochen Hecht
Brad Boyes (14)
Assists: Paul Kariya, Bryce Salvador