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Isner loses to Harrison in Sydney

Updated: January 9, 2013, 1:45 AM ET
Associated Press

SYDNEY -- Top-seeded John Isner lost 6-4, 6-4 to fellow American Ryan Harrison in the second round of the Sydney International on Wednesday.

The exit of Isner, who was promoted to the No. 1 seed after Jo-Wilfried Tsonga and Richard Gasquet withdrew, followed two more injury withdrawals: No. 2 and 2011 Sydney champion Giles Simon (neck) and No. 6 Radek Stepanek (back).

Isner, who withdrew from the Hopman Cup mixed team competition in Perth last week with a right knee injury, lasted ...

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